Which symptom is not typical of extrapyramidal symptoms and might indicate another issue?

Which symptom is not typical of extrapyramidal symptoms and might indicate another issue?

• A. Dystonia
• B. Akathisia
• C. Tardive dyskinesia
• D. Weight gain

Answer: (D)

Extrapyramidal symptoms are motor side effects caused by dopamine D2 receptor blockade in the nigrostriatal pathway. They show up as dystonia (sustained muscle contractions, often in the neck or face), akathisia (inner restlessness and inability to stay still), parkinsonism (trigor, rigidity, bradykinesia), and tardive dyskinesia (late-onset, involuntary movements of the face, tongue, or limbs). Weight gain, on the other hand, is a metabolic side effect rather than a motor symptom. It reflects changes in appetite and energy balance linked to certain antipsychotics and can signal metabolic risk, not an extrapyramidal motor disruption. So the symptom not typical of EPS is weight gain.

Extrapyramidal symptoms are motor side effects caused by dopamine D2 receptor blockade in the nigrostriatal pathway. They show up as dystonia (sustained muscle contractions, often in the neck or face), akathisia (inner restlessness and inability to stay still), parkinsonism (trigor, rigidity, bradykinesia), and tardive dyskinesia (late-onset, involuntary movements of the face, tongue, or limbs). Weight gain, on the other hand, is a metabolic side effect rather than a motor symptom. It reflects changes in appetite and energy balance linked to certain antipsychotics and can signal metabolic risk, not an extrapyramidal motor disruption. So the symptom not typical of EPS is weight gain.